The present invention provides a pharmaceutical composition comprising a protein having \u03b1-galactosidase activity for treating Fabry disease, which causes no allergic side effect, which is highly stable in blood and which can readily be taken up by a cell of an affected organ. The DC motor has a rotating drive shaft, supported at its free end. The packet generator further provides variable time spacing between column and row addresses and data packets. A ratio of cylinder volumes from BDC to TDC for either one of the expansion cylinder and compression cylinder is fixed at substantially 26 to 1 or greater. The removable retention member is then removed to expose a surface of the microelectronic device.