A system is provided that performs automatic variable zooming. The configuration of the reference illuminator and cameras is such that, at least one camera is coaxial with a reference illuminator and at least one camera is non-coaxial with a reference illuminator. The other such data entry function is use of the fingertip for point and click. This invention is also directed to methods for treatment of aneurysms, arteriovenous fistulae, arteriovenous malformations, tumors, and other vascular diseases using the compositions described herein.