The present document describes a pharmaceutical composition as well as methods to improve organ function using a high dose of insulin and maintaining normal glycemia. The filter has an adsorbent for adsorbing impurities selected from the group consisting of a higher hydrocarbon, ammonia, an odorous substance, hydrogen sulfide and a mixture of two or more of these substances. Viewing from an upper surface of the boat, the second bottom surface is located in a position lower than the first bottom surface. The PWM controller receives the sampling signals and transmits the sampling signals to the processor. The inner ring is connected with a second rotating shaft that is connected with the reverse rotating roller. , a legacy transport, into data corresponding to a service for one or more subscriber devices.