A system and method for developing, deploying, managing and monitoring a web application in a single environment is disclosed herein. The platform-neutral layer substantially emulates the native platform of ported code and provides a platform-neutral interface to the ported code. The underfill detection system switches the amplitude of the excitation signal. The antenna embedded within the monolithic structure can be arranged to have a substantially spiral, helical, fractal, meandering or planer serpentine spiral shape. The fusion proteins are substantially non-aggregating and suitable for therapeutic, diagnostic andor research applications.