An impeller has an impeller axis, a first blade support, a second blade support, a third blade support, a plurality of first blades extending between the first blade support and the second blade support, and a plurality of second blades extending between the second blade support and the third blade support. The current source section has at least one current source block comprising a plurality of current sources, each of which outputs an output current. The manufacturing method of the color filter substrate comprises: coating a common electrode layer on a base substrate for forming the color filter substrate; and forming common electrodes of different thicknesses for the color filter substrate units of different sizes by a patterning process. Furthermore, by modification of the amino acid sequence, a protein which can more efficiently produce amoxycillin could be obtained. To evacuate this reservoir, a means for altering pressure is provided that is able to function in hydrant systems that employ a vacuum breaker.