Hydraulic binders, such as cements, mortars with enhanced aging properties, are described. In illustrative embodiments, diindolylmethanes, C-substituted diindolylmethanes, and analogs thereof have been described, which when administered either alone, or in combination with other anti-cancer or anti-tumorigenic compounds, provide new therapies for the treatment of cancer. An inner conductor is formed on the inner surface of the inner-conductor-formed hole.