A composition including a purified lipid cell-wall component or analog or derivative thereof and a suitable pharmaceutical carrier, medium, excipient or adjuvant is described. The device may determine that depression is present by analysis of heart rate variability measured using the cardiac sensing channels of the device andor by detection of blood-borne factors that are associated with depression. A flange on the lid forms an L-shaped slot. If the medical care cannot be validated, the feedback includes the reasons for the failure to validate, and any supporting materials for the lack of validation. According to the invention, such an electronic circuit comprises means for generating a decoding clock using a counter powered by an internal clock, and repeating cycles including incrementation of the said counter until detection of a transition in the said data signal, followed by decrementing the said counter down to zero.