The invention provides a gene delivery vehicle and a gene of interest comprising at least one Ad35 element or a functional equivalent thereof, responsible for avoiding or diminishing neutralizing activity against adenoviral elements by the host to which the gene is to be delivered. The bridge comprises a first bridge module linked to the first communications network and a second bridge module linked to the second communications network. The retro-reflector is preferably in a form of a corner cube array and has light absorbing surface portions at borders of the smallest unit structures.