1460506857-ae0f81a4-e1bf-4c94-bd9a-b8e121282086

The present invention relates to a one-pot process for preparing a compound of formula I: I; by reacting a compound of formula II with a compound of formula III: in the presence of a suitable solvent, a suitable base, a palladium catalyst and a suitable ligand. The present invention specifically provides isolated peptide and nucleic acid molecules, methods of identifying orthologs and paralogs of the secreted peptides, and methods of identifying modulators of the secreted peptides. A back wall of the body may be constructed of a heavy-duty fabric and may also include a pocket or cup holder.