Systems, methods, and computer software for operating a device can be used to operate the device in multiple modes. In an exemplary method a metal film is formed on both surfaces of a piezoelectric wafer, followed by application of photoresist. Accordingly, the development of potent, selective, small molecule agonists, partial agonists, and antagonists of FXR would be an important step in further deconvoluting FXR physiology. Resistive layers, each resistive layer including a first region are disposed in the first through region, a second region disposed in the second through region, and a third region disposed in the trench.