The present invention is generally related towards methods for preparing and using a more stable synthesis catalysts. In one embodiment of the invention, the system-on-chip includes a controller and one or more clock gating units. The device may also include a protection box to be buried in the building material, a dielectric material enclosed in the protection box, and connection terminals protruding from the protection box. IOP has wide diurnal fluctuation, and is dependent on body posture, so the occasional measurements done by the eye care expert in clinic can be misleading. The device is particularly useful in converting multi-well microplates to low sample-volume vessels for automated sampling and testing, and allows the hydraulic pressure generated by a hypodermic needle to transport the sample fluid through the sample vessel and out of a bottom-extraction element.