A multi-path switching configuration provides independent switching of multiple circuit paths. Between an upper member having a grid-like upper concave portion on an inside lower surface and a lower member having a grid-like lower concave portion on an inside upper surface are provided intermediate plate members. Methods of using the bis-phenylarsine molecule also are provided. A handle attaches off-center on the holder to increase visualization of and access to the heart valve through a central window. A refresh pulse generating circuit generates a refresh pulse signal in accordance with one of the forced refresh request signal and the all-time refresh request signal selected by the multiplexer and transmits the refresh pulse signal to the memory core circuit.