A method, apparatus and software program is provided for scheduling and admission controlling of real-time data packet traffic. The conjugate according to the present invention has a structure according to the following formula HAS\u2032n wherein M is a residue of the cytotoxic agent, L is a linking moiety, HAS\u2032 is the residue of the hydroxyalkyl starch derivative, and n is greater than or equal to 1, and wherein the hydroxyalkyl starch derivative has a mean molecular weight above the renal threshold. The delay is generated when a capacitor applies voltage to two control transistors in both the SHIFT and OUT blocks, reducing gate control in these transistors and generating a delay in the falling edge of these signals such that the pulse width of the SHIFT signal is reduced and the pulse width of the OUT signal is increased. The directory memory stores a plurality of telephone numbers and data corresponding to each of the telephone numbers. The method is particularly useful for analyzing an image recording layer of a planographic printing plate precursor which comprises a water-insoluble and alkali-soluble resin, an infrared ray absorber, and a colorant.