To provide an organic electroluminescent device that includes an organic functional layer having high luminous efficiency to provide a bright display. Both the mesh unit and the mesh frame are formed integrally together by a base film which has PET and metal foil. The body contains a relay lens and an ocular lens. The body is formed by two separate parts, with the first part formed with an aperture to define an open end of the receptacle and the second part having a solid wall to define a closed end of the receptacle. The extension member has an inner surface which defines a portion of the gas flowpath through the engine. Among other things, the present invention provides methods and compositions for targeting lysosomal enzymes to lysosomes using furin-resistant lysosomal targeting peptides.