A transmission apparatus to hold a lock core of a supplemental lock includes an inner housing, a lock coupler, a latch bolt coupler, a restitution element and a cover. The disk removing device includes a rotary motor for rotating the disk pickup arm, and an arm support shaft which has the disk pickup arm at its distal end portion and which is rotated, together with the arm, by the rotary motor. The 5\u2032 region includes, but is not limited to, 5 to 10 nucleotides chosen from a repeat from a CRISPR locus immediately upstream of a spacer.