Novel substituted 2,4,8-trisubstituted 8H-pyrido2,3-dpyrimidin-7-one containing compounds and compositions, and their use use in therapy as CSBPRKp38 kinase inhibitors. An SP converter 6 outputs N input data applied in series to decoder 5 through first lines L1-L64 dividedly over several times. The controller then drives a system that manipulates the vehicle’s acceleration or deceleration.