Bulk metallic articles having a high-aspect ratio that are formed of bulk metallic glass, that are net-shaped and that are produced under process conditions that maximize the quality and integrity of the parts as well as the life of the mold tool, thus minimizing production costs, and manufacturing methods for producing such articles are provided. Said compound is a cephalosporin antibiotic having very strong antibacterial activity which exhibits superior characteristics physically, chemically and pharmaceutically. An output parameter is sampled a plurality of times within one or more of the segments.