This invention relates to novel heterocycles which are antagonists at the melanin-concentrating hormone receptor 1, also referred to as 11 CBy, to pharmaceutical compositions containing them, to processes for their preparation, and to their use in medicines. The footwear includes an upper and a sole structure secured to the upper. Elements in a multi-row block are configurable to perform a default function and a function of an element in a neighboring row, if the functions are different. The wire is preferably bus ribbon.