A third harmonic laser system includes a fundamental wave resonator for generating fundamental laser beam, a second harmonic laser generator for converting fundamental laser beam to a second harmonic laser beam, and a third harmonic laser generator for mixing the second harmonic laser beam with the fundamental laser beam so as to produce a third harmonic laser beam. The mobile device includes a computing device capable of connecting to a wireless network. Also there are supply containers and supply lines for the casting compound which open into the casting gaps, and an apparatus for generating pressure. Methods for modulating an immune response upon administration of the oligonucleotide are also disclosed. The total capacitance of the capacitor structure can be tuned by programming, temporarily or permanently, the at least one programmable electrical connection. The number n of the trigger transmitters is smaller than the number A of the axle positions, that each axle position is associated to a triggering range of n trigger transmitters.