The subject of the present invention are quinazoline derivatives and their pharmaceutically acceptable salts of general formula, that inhibit a DNA-repairing enzyme, poly polymerase, enabling them to be used for the preparation of pharmaceutical compositions for preventing or treating illnesses where PARP-inhibition yields a beneficial effect. The first component contains nanosized gold particles. , of paper, to achieve a stronger article. The disposable administration set includes adjustment spacers disposed between the plate assembly and the cam followers which adjust the distance between them to keep the device accurate.