The present inventions provide transgenic aloe plants and recombinant constructs for transforming aloe plants, aspects of which, may be applied to other monocots. The orifice has an exit area O, and the heating element has an effective surface area R, wherein a ratio RO is below about 2. A capture device, which can be configured as a snare-like device, can be used to capture the closure element in the left atrium and pull the closure element back through the septal wall in a different, second location, such that the closure element is routed over the PFO. The shiftable valve includes a valve actuator having a contact surface position substantially adjacent to the first spreader surface. Each belt cord extends in a direction intersecting the ply cord. Market conditions for the financial product portfolio are characterized by a zero curve.