Disclosed herein is a method and system for accelerating the generation of pattern indexes. Specifically, the invention relates to small nucleic acid molecules, such as short interfering nucleic acid, short interfering RNA, double-stranded RNA, micro-RNA, and short hairpin RNA molecules capable of mediating RNA interference against VEGF andor VEGFr gene expression andor activity. The printing mode setting acceptance portion accepts a setting operation of printing modes. The calculation unit is arranged to use the value of expiratory flow measured from the person before the fitness exercise for forming the threshold value of the stress parameter.