A system and method for notifying salespersons of customer communications including a target item is provided. The invention also relates to a process for the combinatorial preparation of protein tyrosine phospatase inhibitors possessing a 4-phosphonate cinnamic acidester molecular scaffold. A distributed network-based virtual memory scheme is provided which treats remote memory as another level in the memory hierarchy between very fast local memory and very slow local disks. By performing the one-dimensional spatial modulation, recording the information is possible even if the recording medium is moving in a direction perpendicular or nearly perpendicular to the direction of the spatial modulation.