The present invention relates, generally, to inositol 1,4,5-triphosphate receptors, and, in particular, to methods of modulating the activity of 220 kDa ankyrin-B in cellular localization and physiological function of IP3R. The skate wheel includes a cylindrical outer hub bonded to an outer layer, a cylindrical inner hub, and first and second decorative spacers positioned between the inner surface of the outer hub and the outer surface of the inner hub. To account for this coupling, the read process for a particular memory cell will provide compensation to an adjacent memory cell in order to reduce the coupling effect that the adjacent memory cell has on the particular memory cell. The protective cover described herein can be fastened in place around a rack or pallet containing a stockpile of funnels. Metal salts such as metal alkoxides, metal acetates and metal nitrates may be mixed with the sol-gel precursers.