The laser comprises an active layer with edges cleaved andor dry etched so that the electromagnetic radiation undergoes total internal reflection. A composite charge is placed on a tool spanning a mold cavity, with the centerline of the charge offset from the centerline of the mold cavity. After the engine is cranked, the windings are changed into a Y connection when the ISAD machine changes from motoring to generating and operates a low speeds, such as idle speed. Eigenvalues of the matrix M are then determined and the first Stokes vector is determined by selecting the largest eigenvalue of the matrix M and determining a corresponding eigenvector. Spacers and seals may be provided about the optical fiber between the fiber Bragg gratings. The context-activated protides of the invention are useful in the diagnosis, prophylaxis, and therapy of a broad range of pathological conditions.