Provided is a machine tool which is equipped with a floating mechanism, and the whole of which can be miniaturized and lightened, the floating mechanism being equipped with carriers of loads generated in both radial and thrust directions, resulting in deformation of the floating mechanism being reduced. The valve pin guide defines a guide aperture therethrough. A preferred biosensor is a Guided Mode Resonant Filter Biosensor. Upon a write to the cell, both power switch transistors are turned off, removing bias from the inverter that assists its change of state in a write operation.