The present invention relates generally to multifunctional devices for performing suction, irrigation, and manipulation at an internal site in a subject, and more particularly to enlargeable multifunctional devices for performing such functions while avoiding obstruction during conventional and endoscopic surgery. The lighting system is adapted to illuminate the surface beneath and around the periphery of the aircraft. The invention further discloses methods for producing nanoconjugates that are suitable for a variety of therapeutic, diagnostic and other uses. The ArO2 treatment can be used to create a bottle-shaped structure.