A detector for magnetizable materials operates remotely to determine a amplitude and phase modification of an exciting magnetic field caused by the magnetizable materials. The securing pin 31 is fixed to a metal core 12 of a steering wheel body 11 and supports a bag holder 21 in such a manner that the bag holder 21 selectively proceeds toward and retreats from the metal core 12. The placement of the primary thrust bearing permits it to extend radially to the outer diameter of the housing. Also provided are diagnostic methods for detecting or prognosing diseases, disorders, damage or injury, associated with alterations of the Stanniocalcin compositions of the invention, and to therapeutic methods for treating such diseases, disorders, damage or injury.