Synthetic and semisynthetic bodies having a three-dimensional structure, sized and shaped to resemble apoptotic cells and apoptotic bodies, and having phosphatidyl serine molecules on the surface thereof, are administered to a patient, to alleviate a variety of disorders such as T-cell mediated disorders. Indicia on the flags can be used to indicate and quickly access different topics and sub topics within a document. In contrast to methods in which a surfactant or lipid is added as an excipient, the hydrophobic compound is actually integrated into the polymeric matrix, thereby modifying the diffusion of water into the microparticle and diffusion of solubilized drug out of the matrix.