The invention provides compositions and methods for the treatment and diagnosis of diseases or disorders amenable to treatment through modulation of expression of a gene encoding a Jun N-terminal kinase 1 (JNK1 protein. The architecture comprises a single CPU configured for executing both the instructions of the first set and the instructions of the second set. The device includes a top planar surface with an electrically active region, and a bottom planar surface disposed substantially parallel to the top planar surface. This identification process allows the option pack to store information, drivers and applications on the option pack, so the main unit does not have to use its memory to store information on a large number of option packs. The test IO controller inputsoutputs the test IO signal in synchronism with the internal clock.