Methods and devices for mechanical andor chemical-mechanical planarization of semiconductor wafers, field emission displays and other microelectronic substrate assemblies. The process is useful for alkylating the C-3 position of indoles that contain acid-sensitive substituents at the N-1 position. Powder flows from a powder source through a powder channel to discharge a powder stream. The bottom of the Hip-Sip is formed to cradle the bulb of stemware to allow the wearer to use two hands for any task at hand.