The present invention provides mutant presenilin 1 and presenilin 2 polpeptides and polynucleotides encoding the polypeptides and methods for their production by recombinant and PCR techniques are disclosed. Bags containing the composite may also be used. A slot disposed in a lower portion of the housing and also aligned generally transverse to the length of the cables is adapted to receive a structural support member for supporting the housing and cable. Placement of one or more elements in the graphical diagram may be adjusted in response to the editing based on determined forces applied to the one or more elements in the edited graphical diagram based on the said editing, resulting in an adjusted edited graphical diagram.