A method of bonding wire between first and second bonding points with a bonding tool, such as a capillary, is disclosed. A content opportunity may include an advertising slot in a programming stream. The clutch device and the actuating device are integrated into the rotor of the electrical machine and the actuating device includes an electrical eddy-current brake with a brake stator and a brake rotor, the brake rotor having at least one electromagnet with a coil and a core, the coil and the core being arranged concentrically in relation to each other. The top layer is coupled to the middle layer and the middle layer is coupled to the bottom layer. The invention further relates to diagnostic and therapeutic methods useful for diagnosing, treating, preventing andor prognosing disorders related to these novel polypeptides. A rotating mechanism rotates the platen assembly with respect to the chassis.