A universal tablet and smart phone holder includes an enlarged soft core, an upper tip section; an elongate spine element extending at least partially through the soft core and to the tip section. The obligately anaerobic lactic acid bacterium of the present invention has been artificially mutated from being facultatively anaerobic to being obligately anaerobic and, furthermore, is capable of being transformed by an expression vector having introduced thereinto a gene for expressing an active protein useful for the treatment of a disease that is in an anaerobic environment. An object in the area of interest is filtered along an object trajectory to adapt motion of the object to permit display of the acquisition rate on a display device having a refresh rate other than the acquisition rate.