Methods of growing crystals of free, antibiotic complexed, or ribosomal substrate complexed large ribosomal subunits, coordinates defining the three-dimensional atomic structure thereof and methods of utilizing such coordinates for rational design or identification of antibiotics or large ribosomal subunits having desired characteristics are disclosed. The filtering media comprises a transparent sheet affixed to the display merchandiser as well as about any fluorescent lighting disposed within the merchandiser. The detecting light emission from the LED is controlled to turn off once the document is successfully detected. The method is thus markedly advantageous from an economical view point as a commercial process for producing oxygen-containing organic compounds such as an aromatic alcohol, a ketone, an aldehyde, a carboxylic acid and an epoxide. If the identified intruder is in fact a trusted node, the security level is returned to a lower setting.