First and second semiconductor regions are formed apart from each other on a semiconductor body. Electrical interconnects are held to a minimum in length by making efficient use of polyimide or polymer as an inter-metal dielectric thus enabling the integration of very small integrated circuits within a larger circuit environment at a minimum cost in electrical circuit performance. Applying a negative bias voltage to adjacent or proximate memory cells shuts off nearby cells to isolate current that may come from over-erased memory cells during a read, program, or erase operation. Analysis of the low frequency variations may yield information about the nature of service-affecting conditions allowing conditions, such as un-terminated or poorly-terminated extensions to be identified. 5 weight percent impurities, and iron. The prosthetic heart valve may be installed over the existing calcified leaflets, and a pre-dilation valvuloplasty procedure may also be utilized.