Various embodiments of the present invention provide for an agglomerate comprising at least one active pharmaceutical agent and at least one excipient; wherein at least about ninety percent of the at least one active pharmaceutical agent have a particle size of less than about 2 \u03bcm. The novel comparator includes a first circuit for comparing first and second input signals and in accordance therewith generating first and second output signals, and a second circuit for adding an adjustable current to the first output signal such that the comparator is in a transition state when the first andor second input signals are at desired levels. A path deflector having a curved path is used in at least one of the paths in order to reduce the pathlength difference, thereby increasing the overlapped amount.