A flexible stand-up package having a releasably securable closure, a fitment pour spout and a handle. Further, a joint angle of the joint of the subject is measured by a sensor. The computing system includes a memory management system interfaced to the segment-addressable memory, the memory management system including one or more memory pool tracking lists configured to track usage of the plurality of memory pools. % of at least one vinyl ester of an aliphatic carboxylic acid containing an acyl moiety having 2 to 22 carbon atoms ; c) from about 0 to about 1 wt.