Systems and methods manually process blood and blood components in sterile, closed environments, which further condition the blood components for subsequent pathogen inactivation processes. In one embodiment, a flap of a flexible material portion of an endovascular graft is folded about a portion of an expandable member to form a loop portion. In response to receiving the request, an IdP instance is selected, preferably using one or more criteria, such as user proximity, instance load, instance availability, the existence of a prior IdP binding, or the like.