A controlling device such as a remote control has programming for transmitting a signal response to a plurality of control environments, each environment including a signaling device. The cap portion includes a transverse aperture and cooperates with the body to define a longitudinal aperture and a catch-receiving cavity. The e-mail pager may send information in its native format to a service that acts as an intermediary. Such compositions have the advantage of treating the entire gastro-intestinal tract since the active ingredient is not removed from the tract via absorption.