A pharmaceutical dosage form adapted to supply a medicament to the oral cavity for buccal, sublingual or gingival absorption of the medicament which contains an orally administrable medicament in combination with an effervescent for use in promoting absorption of the medicament in the oral cavity. A suitable template or substrate is selected and implanted with foreign ions over a desired area to create ion implanted material. The method also can include collecting performance metrics for each of the cache servers in the respective tier nodes of the n-Tier cache and identifying a cache server amongst the cache servers in respective tier nodes of the n-Tier demonstrating a performance likely to breach at least one term of an SLA. The present invention enables sample preparation and handling for diagnostic assays and biochemical analysis in an array format, and the functional integration of these operations. Based on the comparison result, translation dictionary parts differing from the saved translation dictionary parts are determined to be un-obtained parts.