A smoking article, such as a cigarette, includes a lighting end and a mouth end. The present invention further provides methods of preparing stable pharmaceutical compositions of aliphatic amine polymers such as for example Sevelamer HCl, preferably in tablets dosage forms. The protection substrate is placed on the first wafer mold, is mechanically bonded with the first wafer mold using a first adhesive layer, and includes wiring layers facing the first pads. A member is slidably mounted on the necked down portion and provides means to selectively vary the size of the loop.