The present invention provides a light guide plate having reduced hot spots comprising an input surface for receiving light from a plurality of discrete light sources, an output surface for emitting light, a bottom surface opposing to the output surface, and an end surface opposing to the input surface. Web oriented features associated with the candidate keywords andor phrases are also utilized to analyze the web documents. In addition, a dielectric layer is formed between the embedded stressor and the semiconductor region under the buried oxide layer, which is located directly beneath the channel to suppress junction capacitance and leakage. If artificial blood plasma is substituted for whole blood, the concern would be careful monitoring for internal and external bleeding as artificial blood plasma does not clot.