The present invention relates to the discovery that non-traditional export of certain pro-inflammatory cytokines lacking a signal sequence from a cell can be inhibited by copper chelation andor administration to the cell of a truncated form of S100A13 lacking the basic residue portion. This Abstract is not intended to define the invention disclosed in the specification, nor intended to limit the scope of the invention in any way. The wettability is analyzed based on whether a portion of the material floats on or sinks into the fluid. Processing decisions for the subsequent message are based on the presence of the hint indicator. Otherwise, the client sets a dirty flag. In one implementation, a network device may receive a request to register a client device for IMS services.