A method and apparatus for selectively photobleaching or killing pigmented tissues by photochemically converting pigments in the tissues using light and specifically two-photon excitation. Upon sintering, the reactive binder precursor reacts with at least one gaseous, liquid or solid reactant to create a reaction bond that binds the refractory ceramic oxide grains. Changes to shared memory are committed if no other thread has accessed shared memory while the asynchronous method executed. The register device includes a depth that is adapted to hold all instruction packets from the central processing unit without presenting delays due to full conditions. The locking device is arranged in such a way that it is effective at a distance from the final position. Methods and kits are also disclosed herein.