The present invention is directed to compounds and methods for the treatment of metastatic disease. The inventive composition exhibits low smoke generation. The system uses a three dimensional target disposing in a fixed position relative to the subject, and obtains a sequence of video images of a region of interest of a subject while the C-arm is moved manually or by a scanning motor. The contactless power transfer system is disposed within pressure isolation cavities of a sub-sea assembly and configured to transfer power between a power source and a load.