A road plate securing assembly for a roadway surface includes an assembly frame comprising a plurality of assembly frame members having various lengths and adapted for attachment to the roadway surface in end-to-end relationship with respect to each other, a plate opening defined by the assembly frame members and a plurality of road plates seated in the plate opening. The polymer carriers and conjugates enable targeted transport notably of anticancer drugs into solid tumors in which biodegradation, the associated controlled drug release and subsequent elimination of polymer carrier from the organism are provided. The second circuit linearly transforms the partial key by directly using a transformation result from the non-linear transformation unit. The HNB inter-works between the user plane and control plane location solutions. The printer may be equipped with a controller for communicating according to the printing protocol. The other end of the intermediate element is pivotally attached to the operation frame.