A system and method for creating a super-resolution image using an image capturing device. The soluble, refolded proteins produced by the novel methods can then be modified to increase their effectiveness. The length of the lower frame may be adjusted enabling the end members to pivot inwardly from an unfolded position toward a folded position and reduce the spacing between the upper and lower frame rails. The holder is movable between a retracted position where the reference sample is held below the chuck surface and an extended position, such as where the surface of the reference sample is co-planar with the wafer surface. 05 gcc and a basis weight between 25 and 250 gsm. The rod-shaped endoscope body is provided therein with a light emitter, an observing system, a transmitter for transmitting a radio wave which carries an image formed by the observing system, and a power supplying device.