Disclosed are multibinding compounds which are \u03b22 adrenergic receptor agonists and are useful in the treatment and prevention of respiratory diseases such as asthma, bronchitis. A controller of the control apparatus determines a first operating point at which a total fuel consumption amount is minimized as an optimal operating point, such that the total fuel consumption amount is obtained by adding an amount of a fuel consumed by an exhaust purifying device disposed in an exhaust system to an amount of a fuel consumed by the engine for generating a required output. Hardwood layers, such as for example eucalyptus-containing fiber layers, are provided on the outside surfaces of each ply and also on the interface of one or more plies.