A harmonic generation circuit compares audio data supplied from the outside every sample, detects a top-peak and an under-peak of the audio data on the basis of the comparison outputs, and detects patterns of the comparison output between continuous top-peak and under-peak. The constrained interleaver cause the minimum distance of the serial concatenated code to increase above the minimum distance of the inner code alone by adding a constraint that forces some or all of the distance of the outer code onto the serially-concatenated code. Using a second arrangement, it is possible to receive third and fourth radiations from the structure associated with the first and second radiations and a fifth radiation received from a reference. The polyester film is advantageous because it allows for exterior surface coatings to be applied. These compounds inhibit p34cdc2cyclin Bcdc13 kinase and protein tyrosine kinase pp60c-src and can be used for treatment of hyperproliferative diseases, for example tumor diseases, and diseases which respond to inhibition of the activity of protein tyrosine kinase pp60c-src, in particular osteoporosis.